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    Work-Related Diseases

    Find information on occupational work-related diseases including diseases, category and group, synonyms, severity, latency, risk factors, signs and symptoms, diagnosis, prognosis, and treatments and options. 

    Pentachlorophenol, acute toxic effect

    Occupational Disease Pentachlorophenol, acute toxic effect

    Pentachlorophenol, acute toxic effect Category Acute Poison

    Pentachlorophenol, acute toxic effect Severity

    Acute-Moderate

    Pentachlorophenol, acute toxic effect Synonyms

    PCP poisoning

    Information on Pentachlorophenol, acute toxic effect Symptoms, Diagnosis, Prognosis, Screening and Imaging

    Hyperthermia is the major symptom in patients acutely poisoned by PCP. In severe poisonings, muscle spasms and rigidity, as well as seizures, may occur. The dinitrophenols, noted for staining the skin yellow, can also cause uncoupling of oxidative phosphorylation. [ATSDR Case Studies # 23] Most cases of severe occupational poisoning have occurred after dermal absorption. Heat stress increases the risk of a serious outcome in workers who develop hyperthermia from PCP poisoning. [EPA Pesticides] Acute PCP poisoning has been reported in workers exposed to liquid formulations of PCP from: 1) dipping wood, 2) immersing hands, or 3) spraying PCP to kill mollusks. Chronic occupational poisoning has been reported in sawmill workers. [Jorens PG, Schepens PJ. Human pentachlorophenol poisoning. Hum Exp Toxicol 1993 Nov;12(6):479-95]

    Pentachlorophenol, acute toxic effect Latency

    None

    Pentachlorophenol, acute toxic effect References

    http://ace.orst.edu/info/nptn/rmpp.htm

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