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Category Archives: Lymph Node
Acute Lymphadenitis
Acute Lymphadenitis
Acute infection of lymph node from draining an infected focus.
Acute lymphadenitis consists of:
Neutrophils
Necrosis
Abscess formation
Acute lymphadenitis is seen in:
Bacterial infections
Reactive lymphadenopathy
Reactive lymphadenopathy
Reactive lymphadenopathy has five different architectural patterns. Most changes are a mixture of the five patterns.
Hyperplasia
Follicular Hyperplasia
Follicular hyperplasia consists of:
Increased number of B cell germinal centers
Increased size of B cell germinal centers
Follicular hyperplasia is seen in:
Adult-onset still disease
Systemic lupus erythematosus
Kikuchi-Fujimoto disease
Kimura disease
Cat-scratch disease
Toxoplasmosis
Castleman disease
Syphilis (also with a thick capsule from fibrosis and many plasma cells in the medullary region)
HIV (lymphadenitis)
Rheumatoid arthritis (rheumatoid lymphadenopathy)
Diffuse Hyperplasia
Diffuse hyperplasia consists of:
Hyperplasia of the paracortical region, with expansion of T-cell areas.
Diffuse hyperplasia is seen in:
Whipple disease
Viral adenitis (EBV, CMV, Herpes, Vaccinia)
Phenytoin lymphadenopathy (drug)
Post-transplant lymphoproliferative disorder
Rosai-Dorfman disease
Sinus Hyperplasia
Sinus hyperplasia is:
Increased cellularity within medullary sinuses
Sinus hyperplasia is seen in:
Chronic inflammation
Rosai-Dorfman disease (with massive lymphadenopathy and CD68 and S-100 positive histiocytes)
Posted in Lymph Node
Tagged , Diffuse hyperplasia, Follicular hyperplasia, Lymph node hyperplasia, Sinus hyperplasia
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Lymph Node Architecture
Lymph Node Architecture
Lymph nodes consist basically of four compartments: Primary and secondary follicles found near the capsule, paracortex which surrounds the follicles, medullary region and sinuses.
Lymph Nodes in Surgery
Lymph Nodes in Surgery
Lymph nodes are the most accessible of the lymphoid tissues and lymphoreticular system as they are often found close to the skin and are therefore easily removed for pathological examination.
Posted in Lymph Node
Tagged , Lymph Nodes in Surgery, Lymph nodes surgery, Removal of lymph nodes during surgery
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Lymphoreticular system
Lymphoreticular system
Lymph nodes are part of the lymphoreticular system, which consists of lymphoid tissue collections. Tissues included in the lymphoreticular system include the adenoids, tonsils, thymus, spleen and Peyer patches of the gut, as well as lymph nodes. Lymph nodes are the most widely distributed of the lymphoid tissues.
Castleman’s Disease
Castleman’s Disease
