DNA methylation is a chemical modification of DNA that does not alter the original DNA sequence. DNA methylation can be inherited or cannot be. The methylation changes can also be added and removed without ever altering the genetic code. DNA methylation is part of the epigenetic code. DNA methylation occurs when a methyl group is added to DNA, to the 5th carbon of the pyrimidine ring of the nucleic acid base, cytosine. Methylation occurs at CpG dinucleotides found at CpG islands in promoters.
| CellCentric Epigenentics - http://www.cellcentric.co.uk/epigenetics.htm CellCentric is dedicated to progressing our understading of the mechanisms behind epigenentics. CellCentric is established as one of the leaders in unravelling epigenetic control mechanisms and translating this understanding into commercial opportunities. - [Read more] |
| CpG Island Searcher - http://www.uscnorris.com/cpgislands/ CpG island Searcher looks through DNA sequences for CpG islands and generates a graphical output. - [Read more] |
| Methylator - http://bio.dfci.harvard.edu/Methylator/ Methylator predicts whether CpG in a DNA sequence are likely to be methylated or not. - [Read more] |
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