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Category Archives: Appendix
Appendix Carcinoid Tumors
Appendix Carcinoid Tumors
Gross: tip, < 1 cm; gray or yellow, firm, intramural nodule
Histology:
1) insular (nests)
2) trabecular
3) adenocarcinoid
a) tubular
b) goblet cell (mucicarmine, PAS-D, Alcian Blue)
Treatment:
Appendectomy: ? if < 1cm
Indications for right hemicolectomy:
1. > 2 cm
2. positive margin
3. mesoappendiceal spread
Poor prognosis: >2 cm, mesoappendix invasion
goblet cell carcinoid (mucicarmine, CEA +)
Posted in Appendix
Tagged Appendix adenocarcinoid, Appendix adenocarcinoma, Appendix carcinoid tumors, Appendix carcinoma, Appendix tumor, Appendix tumors, Appendix tumour, carcinoid, Carcinoid Tumors, Goblet cell carcinoid
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Mucocele
Mucocele
Mucocele of the Appendix
Definition:
-dilated lumen filled with mucous
Causes of mucocoele:
1. mucinous hyperplasia (looks like hyperplastic polyp)
2. mucinous cystadenoma
3. mucinous cystadenocarcinoma
4. obstruction of the appendix (eg. fecolith, tumour)
Posted in Appendix
Tagged Appendix, Appendix Mucocele, Dilated lumen, Mucocele, Mucocele of the appendix
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Pseudomyxoma Peritonei
Pseudomyxoma Peritonei
- extravasation of mucin into abdomen
- thought to be clonally derived from associated mucinous tumor, usually of appendix
- also associated ovarian mucinous tumors (thought to be metastases from appendix)
Appendix Mucinous Cystadenocarcinoma
Appendix Mucinous Cystadenocarcinoma
- like ovarian tumor
- associated with pseudomyxoma peritonei, particularly if ruptures
Gross appearance: resembles cystadenoma
Histology
- complex papillary fronds
- stratification
- destructive invasion wall
Posted in Appendix
Tagged Appendix, appendix cancer, Appendix Mucinous Cystadenocarcinoma, Appendix tumor, Mucinous cystadenocarcinoma
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Appendix Mucinous Cystadenoma
Appendix Mucinous Cystadenoma
- intestinal type epithelium with minimal atypia
Posted in Appendix
Tagged Appendix, Appendix Mucinous Cystadenoma, Mucinous cystadenoma
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Mucinous Hyperplasia
Mucinous Hyperplasia
Also known as hyperplastic polyp
- looks like a colonic hyperplastic polyp
Simple mucocele
Simple mucocele
- obstructed appendix with intraluminal mucin accumulation
Posted in Appendix
Tagged Intraluminal mucin, Mucocele, Obstructed appendix, Simple mucocele
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Mucous Lesions of the Appendix
Mucous Lesions of the Appendix
• Simple mucocele
• Hyperplastic polyp / mucinous hyperplasia
• Mucinous cystadenoma
• Mucinous cystadenocarcinoma
Posted in Appendix
Tagged Appendix Mucous Lesions, Mucinous cystadenocarcinoma, Mucinous cystadenoma, Mucocele
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Fibrous Obliteration
Fibrous Obliteration
Gross appearance
- firm white tip
Histology
- spindle cells and myxoid component (neural HP)
Immunohistochemistry
S100, chromogranin, NSE
Enterobius Vermicularis
Enterobius Vermicularis
Clinical presentation
- pinworm, ages 7-11, usu incidental
Histology
- cross section has narrow lateral cuticular alae; causes granulomas
Posted in Appendix
Tagged Enterobius Vermicularis, parasite, Pinworm, Pinworm infection
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