Category Archives: Anus

Anal Cancer

- mainly consists of squamous cell carcinoma within the anal canal and anorectal junction.

Anal cancer squamous cell carcinoma variants:

                 -Basaloid (cloacogenic) type

                -large cell keratinizing type

                -large cell non-keratinizing type

The above is the old classification. Not used anymore as many of the tumors show a mixture of morphologies. Types that are worth remembering are:

                -squamous cell carcinoma with mucinous microcysts

                -small cell ( anaplastic ) carcinoma -  not small cell neuroendocrine carcinoma

                BOTH of the above carcinomas, have a less favorable prognosis

                -veruccous carcinoma -  behaves better than regular squamous cell carcinoma and only invades locally without metastasizing